Fuzzy Simulation of Drug Delivery System through Valve-Less Micropump
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Abstract
This research article presents Fuzzy estimation of fluidic parameters for valve-less micropump. The drug delivery system is incomplete without a micropump. The proposed Fuzzy controller micropump (MDDFC) consists of three inputs and two outputs. The investigation through Fuzzy simulation is carried out in order to evaluate the drug flow rate and drug speed. The simulation based on the real time conditions for fluidic parameters. Results are in good agreement with previous researches. The difference between simulated and calculated results is just 1 µl/min for drug flow rate and 0.01 milliliter/sec for drug speed
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Pakistan Journal Emerging Science and Technologies (PJEST) in collaboration with Govt. Islamia Graduate College Civil Lines Lahore, Pakistan is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
References
M. W. Ashraf, S. Tayyaba, and N. Afzulpurkar, "Micro electromechanical systems (MEMS) based microfluidic devices for biomedical applications," International journal of molecular sciences, vol. 12, pp. 3648-3704, 2011.
E. Stemme and G. Stemme, "A valveless diffuser/nozzle-based fluid pump," Sensors and Actuators A: physical, vol. 39, pp. 159-167, 1993.
A. Z. Kouzani, M. Ivankovic, M. Fielding, A. Kaynak, C. Yang, W. Duan, et al., "Design and construction of a micropump for drug delivery applications," in IEEE/ICME International Conference on Complex Medical Engineering, 2010, pp. 182-187.
S. Tayyaba, M. Ashraf, M. Ishaque, and N. Afzulpurkar, "Numerical simulation of piezoelectricaly actuated valveless micropump for hemofiltration system," in 2012 9th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology, 2012, pp. 1-4.
G.-H. Feng and E. S. Kim, "Piezoelectrically actuated dome-shaped diaphragm micropump," Journal of microelectromechanical systems, vol. 14, pp. 192-199, 2005.
M. Koch, N. Harris, A. G. Evans, N. M. White, and A. Brunnschweiler, "A novel micromachined pump based on thick-film piezoelectric actuation," Sensors and Actuators A: Physical, vol. 70, pp. 98-103, 1998.
C. Y. Shen and H. K. Liu, "Fabrication and drive test of piezoelectric PDMS valveless micro pump," Journal of the Chinese Institute of Engineers, vol. 31, pp. 615-623, 2008.
A. Olsson, G. Stemme, and E. Stemme, "A valve-less planar fluid pump with two pump chambers," Sensors and Actuators A: Physical, vol. 47, pp. 549-556, 1995.
M. J. Afzal, S. Tayyaba, M. W. Ashraf, M. K. Hossain, M. J. Uddin, and N. Afzulpurkar, "Simulation, fabrication and analysis of silver based ascending sinusoidal microchannel (ASMC) for implant of varicose veins," Micromachines, vol. 8, p. 278, 2017.
M. J. Afzal, F. Javaid, S. Tayyaba, M. W. Ashraf, C. Punyasai, and N. Afzulpurkar, "Study of Charging the Smart Phone by Human Movements by Using MATLAB Fuzzy Technique," in 2018 15th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology (ECTI-CON), 2018, pp. 411-414.
M. J. Afzal, M. W. Ashraf, S. Tayyaba, M. K. Hossain, and N. Afzulpurkar, "Sinusoidal Microchannel with Descending Curves for Varicose Veins Implantation," Micromachines, vol. 9,p. 59, 2018.
M. J. Afzal, S. Tayyaba, M. W. Ashraf, M. K. Hossain, and N. Afzulpurkar, "Fluidic simulation and analysis of spiral, U-shape and curvilinear nano channels for biomedical application," in 2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO), 2017, pp. 190-194.
M. J. Afzal, F. Javaid, S. Tayyaba, M. W. Ashraf, and M. K. Hossain, "Study on the Induced Voltage in Piezoelectric Smart Material (PZT) Using ANSYS Electric & Fuzzy Logic," 2020.
S. Tayyaba, M. W. Ashraf, Z. Ahmad, N. Wang, M. J. Afzal, and N. Afzulpurkar, "Fabrication and Analysis of Polydimethylsiloxane (PDMS) Microchannels for Biomedical Application," Processes, vol. 9, p. 57, 2021.
M. J. Afzal, M. W. Ashraf, S. Tayyaba, A. H. Jalbani, and F. Javaid, "Computer Simulation Based Optimization of Aspect Ratio for Micro and Nanochannels," Mehran University Research Journal of Engineering and Technology, vol. 39, pp. 779-791, 2020.
E. Zijlstra, J. Jahnke, A. Fischer, C. Kapitza, and T. Forst, "Impact of injection speed, volume, and site on pain sensation," Journal of diabetes science and technology, vol. 12, pp. 163-168, 2018.